2(Avengers)

An Au where Loki visited Midgard quite often and has his own family there which he went to join forever after his confrontation with Odin(he didn't become the regent and let Frigga to deal with everything as Loki was done with everything and everyone in Asgard).

When he ended up in Midgard, Loki's first action was take the persona he had used during his other stays there as Lokajanani(it means 'mother of the world') 'Loki' Dahl before she went to visit her ex-husband(Daniel 'Dan' Potts), her blood daughter(Viriginia 'Pepper' Potts) and the multiple 'children'(by this I mean that for Loki they are children but for others almost all of them are adults...and I had in mind that some of this kids could be Peter Parker, MJ, Ned, Flash Thompson, Matt Murdock, Wade, a few of the most loved villains, Erik Killmonger, etc).

How this would change canon? Loki wouldn't send the Destroyer after Thor, there would be no suicide or mass murder attempt(Loki probably went to therapy after making sure everyone she considers family was fine...which she really needs), who comes to Midgard would for sure not be Loki(unless whoever it is, uses an illusion spell to make it look like him) and that who would defeat Thanos would be Loki and her army of kids who while not all sharing blood are vicious annoying little shits that do not fear anyone especially someone who will try to kill half of the universe.

I know this idea makes no sense but anything else(including filling plot holes) is up to whoever decides to write this.